Synergetic Relief: Cannabinoids & Opioids

Many medical professionals face challenges in ensuring the safe use of opioids for their patients. However, studies propose a novel solution — combining the analgesic properties of cannabinoids with the pain-relieving effects of opioids. This innovative strategy may enhance the overall efficacy and safety of pain treatment.

A 2021 study conducted at 21 medical clinics across Canada investigated the interplay between medical cannabis, prescription opioids, and overall quality of life. With 1,145 Canadian medical cannabis patients participating in this research over a 6-month period, the study reported a baseline opioid use of 28%, which dramatically decreased to 11% after 6 months.

Beyond opioids, participants also experienced substantial decreases in other primary prescription drug classes, accompanied by statistically significant improvements in their overall quality of life.

Another study revealed the potential synergy between cannabinoids and opioids. In a double-blind, placebo-controlled investigation involving healthy cannabis smokers, researchers explored the analgesic effects of combining low-dose oxycodone with smoked cannabis.
The findings revealed a synergistic effect, enhancing pain relief without escalating the abuse potential of cannabis.

‍This breakthrough holds promise for advancing pain management, allowing physicians to potentially prescribe lower opioid doses, thereby reducing the risk of opioid dependence. However, it's important to note that both cannabis and opioids have depressant effects. When combined at non-medical doses, these substances can dangerously suppress the central nervous system. Therefore, healthcare professionals should approach this development with careful optimism.