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The Science Behind Strain Alternatives: Genetic Lineage

Cannabis strains, like people, have genetic ancestry. Each strain inherits its genetic makeup from its parent strains. These parent strains contribute specific traits, including cannabinoid composition, terpene profile, and growth characteristics, to their offspring.

When two cannabis strains share a common parent genetic strain, they possess genetic similarities that manifest in their characteristics. Just as siblings share traits inherited from their parents, cannabis strains with a common genetic lineage exhibit resemblances in their chemical composition and growth patterns.

The shared genetic heritage between two strains results in a degree of consistency in their effects. For instance, if one strain is known for its relaxing properties due to its cannabinoid and terpene profile, a substitute strain with a common parent genetic strain is likely to induce similar effects, albeit with slight variations.

Transitioning between cannabis strains becomes smoother when substituting with a strain sharing a common parent genetic strain. This is because the genetic similarities between the two strains facilitate adaptation for both the cultivator and the patient. Cultivation practices can remain relatively consistent, and patients can expect a familiar experience.

When one strain becomes temporarily unavailable, such as Bacio Gelato, substituting with another strain sharing a common parent genetic strain, such as Jealousy, ensures continuity in characteristics, effects, and quality standards.

Strain substitution can also be therapeutically beneficial in preventing patients from building a tolerance to certain strains (read more in our upcoming NUG).

What is Bx1?

Bx1 is a term indicating first generation back-cross cultivation. This means an offspring plant is cross-cultivated with one of its parents. This is usually done to stabilise genetics or enhance desired characteristics of the final plant. As an example, Parent 1 (P1) and Parent 2 (P2) plants are bred to produce F1. When F1 is bred with either P1 or P2, the product is a Bx1 cultivar.

References
  • 1 Francomano, F.; Caruso, A.; Barbarossa, A.; Fazio, A.; La Torre, C.; Ceramella, J.; Mallamaci, R.; Saturnino, C.; Iacopetta, D.; Sinicropi, M.S. β-Caryophyllene: A Sesquiterpene with Countless Biological Properties. Appl. Sci. 2019, 9, 5420. https://doi.org/10.3390/app9245420
  • 2 Stueber A, Cuttler C. A large-scale survey of cannabis use for sleep: preferred products and perceived effects in comparison to over-the-counter and prescription sleep aids. Explor Med. 2023;4:709–19. https://doi.org/10.37349/emed.2023.0017
  • 3 Weston-Green K, Clunas H and Jimenez Naranjo C (2021) A Review of the Potential Use of Pinene and Linalool as Terpene-Based Medicines for Brain Health: Discovering Novel Therapeutics in the Flavours and Fragrances of Cannabis. Front. Psychiatry 12:583211. doi: 10.3389/fpsyt.2021.583211
  • 4 Szejko N, Becher E, Heimann F et al. Medicinal Use of Different Cannabis Strains: Results from a Large Prospective Survey in Germany. Pharmacopsychiatry 2024; 57(03): 133 - 140. doi:10.1055/a-2261-2269
  • 5 Carrie Cuttler, Amanda Stueber, Ziva D. Cooper et al. Acute Effects of Cannabigerol on Anxiety, Stress, and Mood: A Double-Blind, Placebo- Controlled, Crossover, Field Trial, 15 May 2024, PREPRINT (Version 1) available at Research Square https://doi.org/10.21203/rs.3.rs-4213847/v1
  • 6 Tory R. Spindle, C. Austin Zamarripa, Ethan Russo, Lauren Pollak, George Bigelow, Alexandra M. Ward, Bridget